Claudin-15 overexpression inhibits proliferation and promotes apoptosis of Schwann cells in vitro

• 作 者: Jian-Nan Li Zhan Zhang Guang-Z
• 机 构: China-JapanUnionHospitalofJilinUniversity,SchoolofLifeSciences
• 出 处: 中国神经再生研究:英文版
• 发表日期: 2020年1期
• 关键词: apoptosis Bax cell PROLIFERATION c-Jun Claudin-15 NERVE regeneration peripheral
• 基金项目: This study was supported by the National Natural Science Foundation of China,No.81671220(to SSC),the Scientific and Technological Development Program of Jilin Province of China,No.20160101077JC(to SSC

Our previous experiments have discovered that Claudin-15 was up-regulated in Schwann cells of the distal nerve stumps of rat models of sciatic nerve injury.However,how Claudin-15 affects Schwann cell function is still unknown.This study aimed to identify