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作者对２０１例盘状红斑狼疮的临床、病理与免疫金银染色检测作了分析。结果显示：损害好发于下唇（６０％）。在系统因素中，患消化系统疾病为２５％，占首位。全部病例均经病理证实，其中８例伴有轻度上皮异常增生，３例发生癌变，１例盘状红斑狼疮和扁平苔藓共存。免疫金银染色检测显示：在组织切片的基底膜区除了有Ｆｇ的沉积之外，尚有多类免疫球蛋白或多类免疫球蛋白伴补体Ｃ３的共同沉积。说明盘状红斑狼疮是一种由多种因素引起的自身免疫性疾病，具有癌变可能，盘状红斑狼疮与扁平苔藓共存现象可能提示是一种疾病的不同发病阶段，其机理有待于作更深入的研究。
The authors of 201 cases of discoid lupus erythematosus clinical, pathological and immunological gold and silver staining were analyzed. The results showed that: damage occurs in the lower lip (60%). Among the systemic factors, patients with digestive diseases accounted for 25% of the total, ranking the top. All cases were pathologically confirmed, of which 8 cases with mild epithelial dysplasia, 3 cases of cancer, 1 case of lupus erythematosus and lichen planus coexist. Immunogold-silver staining test showed that in addition to the deposition of Fg in the basement membrane area of the tissue section, there are multiple types of immunoglobulins or co-deposition of multiple types of immunoglobulins with complement C3. Discoid lupus erythematosus is a kind of autoimmune diseases caused by a variety of factors, with the possible cancer, coexistence of discoid lupus erythematosus and lichen planus may suggest a disease at different stages of disease, the mechanism needs to be further Research.