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通过对１１例直肠腺癌及周围粘膜上皮细胞超微结构的电镜观察，对比研究了术前放疗引起的直肠腺癌超微结构的改变。提示放疗后病人出现的不同程度的症状减轻与瘤细胞坏死，瘤体缩小有关；粘液稀便减少与放疗所致的粘膜损伤，特别是杯状细胞的破坏直接相关。为术前放疗理论提供了病理学基础。
By ultrastructural observation of 11 cases of rectal adenocarcinoma and surrounding epithelial cells, ultrastructural changes of rectal adenocarcinoma caused by preoperative radiotherapy were compared. It is suggested that the different degrees of symptoms appearing in patients after radiotherapy are related to the necrosis of tumor cells and the shrinkage of tumors; the reduction of mucous sparse stool is directly related to the mucosal damage caused by radiotherapy, especially the destruction of goblet cells. It provides a pathological basis for the theory of preoperative radiation therapy.