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葡萄糖转化酶1(GLUT1)属于活化的葡萄糖转化蛋白家族(GLUT1~7),在许多肿瘤的葡萄糖摄取中起主要作用。生理状态下GLUT1主要表达在红细胞膜、脑毛细血管内皮(血脑屏障)、外周神经的神经束膜及良性鳞状上皮基底细胞。研究表明,GLUT1在许多葡萄糖代谢率高的实质性肿瘤中有较高的表
Glucose converting enzyme 1 (GLUT1) belongs to the activated glucose conversion protein family (GLUT1-7) and plays a major role in glucose uptake in many tumors. GLUT1 is mainly expressed in the erythrocyte membrane, brain capillary endothelial (blood-brain barrier), perineurial perineurium and benign squamous cell basal cells under physiological conditions. Studies have shown that GLUT1 has a high table in many substantial tumors with high glucose metabolic rates