论文部分内容阅读
对济南市历城区西营镇部分中小学生口服碘油丸引起的以胃肠道症状为主的不良反应进行了调查。结果表明不良反应率为７１．１７％，临床主要表现为腹痛、头痛、恶心，并伴有发热、咽干、头晕、呕吐等．流行病学调查、尿样检测及药品检验结果分析表明，不良反应主要与口服放置过久的碘油丸有关，其具体原因及影响因素是药品成份植物油酸败产物及游离碘所致．建议今后应加强药品管理，生产厂家标明药品失效期，以指导专业人员正确开展ＩＤＤ预防服药工作。
Jinan City Licheng District Xiyang part of primary and secondary school students taking oral iodized oil pills caused by gastrointestinal symptoms-based adverse reactions were investigated. The results showed that the rate of adverse reactions was 71.17%. The main clinical manifestations were abdominal pain, headache, nausea, accompanied by fever, dry throat, dizziness, vomiting and so on. Epidemiological survey, urine samples and drug test results show that adverse reactions mainly with orally administered iodized oil pills too long, the specific reasons and the factors that affect the pharmaceutical composition of vegetable oil rancidity products and free iodine. It is suggested that drug administration should be strengthened in the future, and manufacturers should indicate the expiration date of drugs so as to guide professionals to correctly carry out IDD preventive medication.