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目的 探讨中脑背侧及其周围肿瘤手术后点头、高热、流涎、嗜睡等类恶性综合征的原因及对策。方法 回顾 5例中脑背侧及其周围肿瘤手术后并发恶性综合征病例 ,并结合文献进行分析。结果 16例中脑及其周围肿瘤手术后有 5例出现类恶性综合征表现 ,4例治疗后痊愈 ,1例死亡。结论 中脑及其周围肿瘤手术可能损害中脑及丘脑而引发类恶性综合征。减少牵拉、正确使用电凝及有梗阻性脑积水可能者早期行分流术有可能减轻其损害。一旦术后出现恶性综合征 ,早期支持对症治疗及应用多巴胺类和乙酰胆碱抑制药物仍有较好的预后。
Objective To investigate the causes and strategies of nodding, hyperthermia, salivation, drowsiness and other malignant syndrome after dorsal medulla and its surrounding tumors. Methods A retrospective study of 5 cases with malignant syndrome after operation in the dorsal midline and surrounding tumors was performed and analyzed in combination with the literature. Results Sixteen cases of midbrain and its surrounding tumors showed malignant syndrome in 5 cases after surgery, 4 cases recovered and 1 case died. Conclusion The operation of the midbrain and its surrounding tumors may damage the midbrain and the thalamus and cause malignant syndrome. Reduce traction, the proper use of electrocoagulation and obstructive hydrocephalus may be those who early shunt may reduce its damage. Once the postoperative malignant syndrome, early support symptomatic treatment and the use of dopamine and acetylcholine inhibitory drugs still have a better prognosis.