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目的:探讨慢性阻塞性肺病稳定期采用能全力治疗对免疫功能的影响。方法:选择COPD稳定期患者80例,按观察组和对照组各40例划分,对照组采用长效茶碱类药物常规治疗,观察组则在对照组治疗的基础上加用能全力口服治疗,回顾性分析临床资料。结果:两组治疗前IgG水平、IgM水平、IgA水平、血清白蛋白、前白蛋白、转铁白蛋白检测无明显差异(P>0.05)。治疗后观察组IgG水平、IgM水平显著升高,血清白蛋白、前白蛋白、转铁白蛋白检测恢复较好,与对照组比较有显著差异(P<0.05)。IgA两组变化均不明显(P>0.05)。观察组临床总有效率高于对照组(P<0.05)。结论:慢性阻塞性肺病稳定期采用能全力辅助治疗,有助于改善营养状况和机体免疫功能,从而提高综合治疗的疗效,减少住院次数。
Objective: To investigate the effect of full treatment on immune function in stable COPD patients. Methods: Eighty patients with stable COPD were divided into observation group (40 cases) and control group (40 cases). The control group was treated with long-acting theophylline, and the observation group was treated with oral treatment on the basis of the control group. Retrospective analysis of clinical data. Results: There was no significant difference in serum IgG, IgM, IgA, serum albumin, prealbumin and transferrin before treatment in both groups (P> 0.05). After treatment, the level of IgG and the level of IgM in the observation group were significantly increased, and the levels of serum albumin, prealbumin and transferrin were restored well, which were significantly different from those of the control group (P <0.05). IgA changes in both groups were not significant (P> 0.05). The total effective rate in observation group was higher than that in control group (P <0.05). Conclusion: The stable COPD patients can make full use of adjuvant therapy and improve the nutritional status and immune function, thus improving the curative effect of comprehensive treatment and reducing the number of hospitalizations.