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为了解血清PLA2对急性胰腺炎的临床价值,应用单克隆抗体,免疫组化方法,检测20例急性胰腺炎和15例其他腹痛病人的血清PLA2值。结果发现,所有急性胰腺炎病人(包括出血坏死型和水肿型),在入院当天血清PLA2值均有明显升高,表现为阳性或强阳性,敏感性100%,持续时间3~9天或更长;且在一定范围内随病情变化而变化,可以反应胰腺的损害程度,对胰腺炎的预后判断有一定帮助。其他腹痛病人(胆囊炎、腹膜炎、阑尾炎),PLA2值也有不同程度升高,甚至表现为强阳性。研究表明,PLA2对急性胰腺炎不具有特异性,它只是急性胰腺炎诊断中的一个重要参考指标
To understand the clinical value of serum PLA2 in acute pancreatitis, serum PLA2 levels in 20 patients with acute pancreatitis and 15 patients with other abdominal pains were detected by monoclonal antibody and immunohistochemistry. The results showed that all patients with acute pancreatitis (including hemorrhagic necrosis and edema type), serum PLA2 values were significantly elevated on admission day, showed positive or strong positive, the sensitivity of 100%, the duration of 3 to 9 days or more Long; and within a certain range with changes in the condition changes, can reflect the extent of the damage of the pancreas, the prognosis of pancreatitis have some help. Other patients with abdominal pain (cholecystitis, peritonitis, appendicitis), PLA2 values also increased to varying degrees, and even showed strong positive. Studies have shown that, PLA2 is not specific for acute pancreatitis, it is only an important reference in the diagnosis of acute pancreatitis