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脑静脉血栓形成(CVT)与很多病因和易感因素有关。据报道,凝血酶原基因3′非翻译区核苷酸20210G→A突变能增加深静脉血栓形成和肺栓塞的危险性。本项研究的目的是确定35例CVT患者中凝血酶原基因的多态频率,以此来评定CVT的相关病因或危险因素。198?
Cerebral vein thrombosis (CVT) is associated with many causes and susceptibility factors. It is reported that 3’-untranslated region of prothrombin gene nucleotide 20210G → A mutation can increase the risk of deep venous thrombosis and pulmonary embolism. The purpose of this study was to determine the polymorphic frequency of the prothrombin gene in 35 patients with CVT to assess the etiology or risk factors associated with CVT. 198?