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自1975年甲氰咪胍应用于临床以来,其副作用的报道几乎涉及全身各个系统,但引起心房颤动(房颤)者罕见,笔者遇见1例,报告如下。患者男,51岁,医师。曾患十二指肠球部溃疡并有过出血史,近几天觉上腹部隐痛,于1988年7月15日服甲氰咪胍,每次200mg,每日3次。当服至第三次后3小时,感胸闷、心悸,气短、头昏。既往无心脏病、高血压病和甲状腺机能亢进病史。体检:血压16.0/10.7kPa(120/80mmHg),甲状腺不大,肺部听诊无异常。心界不扩大,心率114次/
Since 1975, cimetidine applied to clinical since its side effects reported almost all body systems involved, but caused by atrial fibrillation (atrial fibrillation) were rare, I met one case, the report is as follows. Male patient, 51 years old, physician. Have suffered from duodenal ulcer and had a history of bleeding, feeling pain in the abdomen in recent days, on July 15, 1988 Cimetidine, 200mg each time, 3 times a day. When served three hours after the third, chest tightness, palpitations, shortness of breath, dizziness. Past history of heart disease, hypertension and hyperthyroidism. Physical examination: blood pressure 16.0 / 10.7kPa (120 / 80mmHg), thyroid is not large, no abnormal lung auscultation. Heart does not expand, heart rate 114 times /