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[目的]探讨老年急性髓细胞白血病(AML)患者合并感染的临床特点。[方法]2005～2009年收治129例急性髓细胞白血病患者,对其中31例老年患者的院内感染发生率、感染部位和危险因素等情况进行回顾性分析。[结果]老年组发生院内感染26例,发生率为83.87%。明显高于非老年组感染发生率为63.27%,差异有统计学意义(P﹤0.05)。感染部位以呼吸系统多见,占61.54%。白细胞减少、化疗诱导阶段是增加感染的危险因素。[结论]老年急性髓细胞白血病患者院内感染发生率高于同期非老年组,预防和控制医院感染是提高AML治疗水平,延长患者生存期的重要措施。
[Objective] To investigate the clinical features of combined infection in elderly patients with acute myeloid leukemia (AML). [Methods] A total of 129 patients with acute myeloid leukemia were enrolled in this study. The incidence, nosocomial infection and risk factors among 31 elderly patients were analyzed retrospectively. [Results] There were 26 nosocomial infections in the elderly group, the incidence was 83.87%. The incidence of infection was significantly higher than non-elderly group was 63.27%, the difference was statistically significant (P <0.05). Infected parts of the respiratory system more common, accounting for 61.54%. Leukopenia, chemotherapy-induced stage is to increase the risk of infection. [Conclusion] The incidence of nosocomial infection in elderly patients with acute myeloid leukemia is higher than that of non-elderly patients in the same period. Prevention and control of nosocomial infection are important measures to increase the level of AML treatment and prolong the survival of patients.