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目的：探讨肾移植术后低镁血症的意义。方法：将４９例肾移植患者按血清镁水平分成两组，比较其２４小时尿镁、血浆胰岛素浓度，并对血清环孢素（ＣｓＡ）浓度与血清镁浓度进行直线相关与回归分析。结果：低血镁主要原因系ＣｓＡ所致，ＣｓＡ浓度与血清镁浓度呈显著负相关，低血镁组血浆胰岛素浓度高。结论：纠正低镁血症有助于减弱ＣｓＡ的肾毒性，控制肾移植后高血压。
Objective: To investigate the significance of hypomagnesemia after renal transplantation. Methods: 49 cases of renal transplant patients were divided into two groups according to serum magnesium levels. Their 24-hour urinary magnesium and plasma insulin concentrations were compared. The linear correlation and regression analysis between serum CsA and serum magnesium concentration were performed. Results: The main cause of hypomagnesemia was CsA. There was a significant negative correlation between CsA concentration and serum magnesium concentration, while hypomagnesemia group had high plasma insulin concentration. Conclusion: Correcting hypomagnesemia can reduce the nephrotoxicity of CsA and control the post-transplant hypertension.