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本文探讨了49例急性白血病患者化疗后白细胞减少发热的原因,并比较了单独应用抗菌素和抗菌素并用抗霉菌药物的治疗效果.化疗后末梢血中中性粒细胞<500/μl,持续1-2周者约60%,持续2-3周者约80%,持续3周以上者几乎达100%并出现发热(T<38℃).49例发热共195例次中,通过血培养明确诊断为败血症者44例次(22%).其中草兰氏阳性菌感染8例次,革兰氏阴性菌感染38例次,其中绿脓杆菌感染者22例次(约占60%),霉菌感染6例次.革兰氏阳性和阴性菌或霉菌交叉感染5例次,细菌和霉菌双重感染2例次.有明确的败血
This article explored the causes of leukopenia in 49 patients with acute leukemia after chemotherapy and compared the efficacy of antibiotics and antibiotics alone with antimycotics.After chemotherapy, neutrophils in peripheral blood were <500 / μl for 1-2 About 60% of the patients were followed up for about 80% for 2-3 weeks, almost 100% for more than 3 weeks and had fever (T <38 ℃) .Among 195 cases of 49 cases of fever, Sepsis in 44 cases (22%), of which 9 cases of gram-positive bacteria infection, gram-negative bacteria in 38 cases, of which 22 cases of Pseudomonas aeruginosa infection (about 60%), mold infection 6 Cases. Gram-positive and negative bacteria or mold cross-infection in 5 cases, bacterial and mold double infection in 2 cases. A clear septicemia