论文部分内容阅读
A complex process including both the innate and acquired immune responses results in allograft rejection.Somechemokine receptors and their ligands play essential roles not only for leukocyte migration into the graft but alsoin facilitating dendritic and T cell trafficking between lymph nodes and the transplant in the early and late stage ofthe aliogeneic response.This review focuses on the impact of these chemoattractant proteins on transplant outcomeand novel diagnostic and therapeutic approaches for antirejection therapy based on targeting of chemokinereceptors and/or their ligands.Cellular & Molecular Immunology.2005;2(5):343-349.
A complex process including both the innate and acquired immune responses results in allograft rejection. Cerechemokine receptors and their ligands play essential roles not only for leukocyte migration into the graft but also in facilitating dendritic and T cell trafficking between lymph nodes and the transplant in the early and late stage of the aliogeneic response. this review focuses on the impact of these chemoattractant proteins on transplant outcome and novel diagnostic and therapeutic approaches for antirejection therapy based on targeting of chemokine receptors and / or their ligands. Cellular & Molecular Immunology. 2005; 2 (5): 343-349.