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在血友病A患者中发现了获得性免疫缺陷综合征(AIDS)病例,加之在经冻干浓缩因子Ⅷ制剂治疗的患者中发生了与获得性免疫缺陷综合征患者中T辅助细胞(Th)和抑制细胞(Ts)的相同变化,故有人认为AIDS的致病因子可经诸如因子Ⅷ等血液制剂而传播。作者共选择43例患者,其中37例是中度或重度血友病A患者,6例是严重的因子Ⅸ缺乏患者,按所用凝血因子制剂的不同,将患者分为四组,第一组20例患者在2年研究期间只用冷沉淀,第二组11例患者主要用冷沉淀,另外还用了9瓶浓缩因子Ⅷ,第三组6例患者只用浓缩因子Ⅷ,第四组6例患者则用浓缩Ⅸ因
Acquired immunodeficiency syndrome (AIDS) cases were found in hemophilia A patients, and in patients with Acquired Immune Deficiency Syndrome T-helper cells (Th) developed in patients treated with lyophilized concentration factor VIII, And suppression of the same changes in cells (Ts), it is considered that the causative agent of AIDS can be transmitted via blood agents such as factor VIII. The authors selected a total of 43 patients, of which 37 were moderate or severe hemophilia A patients, 6 were severe factor IX deficiency patients, according to the different coagulation factor preparations used, the patients were divided into four groups, the first group of 20 The patients were only cryoprecipitated during the 2-year study, the second group consisted of cryoprecipitations in 11 patients, additional 9 vials of concentration factor VIII, the third group of 6 patients received enrichment factor VIII only, and the fourth group of 6 patients Patients are concentrated Ⅸ cause