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本文旨在观察二硫化碳（ＣＳ２）对接触工人促性腺激素和生精功能的影响。工人工作地点ＣＳ２平均浓度（几何均数）为３２．６０±５．１４ｍｇ／ｍ３，约高于国家容许浓度２倍，对１８例长期接触超标浓度的ＣＳ２作业工人进行了血清睾酮（Ｔ），促黄体生成素（ＬＨ），间质细胞刺激素（ＦＳＨ）测定，观察１６名工人精液的某些参数。结果表明：ＣＳ２接触组血清中ＬＨ和ＦＳＨ浓度与对照组比较，显著升高，Ｐ＜０．０１；而ＣＳ２组精子计数、血清Ｔ浓度与对照组相比，明显降低，Ｐ＜０．０５。畸形率高于对照组，但无统计学意义，本研究结果表明，ＣＳ２对接触工人性腺内分泌功能已造成一定的损伤，并降低生精功能。
This article aims to observe the effects of carbon disulfide (CS2) on gonadotrophin and spermatogenic function in exposed workers. The CS2 average concentration (geometric mean) of workers working place was 32.60 ± 5.14mg / m3, which was about 2 times higher than the national allowable concentration. Serum testosterone (T) was measured in 18 CS2 workers exposed to excessive concentrations for long- Luteinizing hormone (LH) and interstitial cell stimulating hormone (FSH) were measured. Some parameters of 16 workers were observed. The results showed that the concentration of serum LH and FSH in CS2 exposure group was significantly higher than that in control group (P <0.01), while the sperm count and serum T concentration in CS2 group were significantly lower than those in control group (P <0.05) . The rate of deformity was higher than that of the control group, but not statistically significant. The results of this study showed that CS2 caused certain damage to gonadal endocrine function of exposed workers and reduced the function of spermatogenesis.