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血清麦氨氨草酰乙酸转氨酶(Glutamic Oxalacetie Transaminase)简称为(G.O.T),为动物组织中活力最大的转氨酶之一,Cohen 氏首先发现动物组织中以心肌,骨骼肌,肝脏含量最为丰富,次以脑、肾、肺、睾丸。转氨基酶在机体内是促使蛋白质在它的中间代谢中完成氨基转移作用上的一种主要物质基础,而 G.O.T.可以转换天门冬氨酸(Asparate)及〆-酮戊二酸(〆-ketoglutarate)之氨基及酮基,而使之合成新的氨基酸——麦氨酸(Glutamate)及新的〆-酮酸一草酰醋酸(Oxalacetate)其反应式:
Glutamic Oxalacetate Transaminase (GOT) is one of the most active transaminases in animal tissue. Cohen first discovered that animal tissues contain most abundant myocardium, skeletal muscle, and liver. Brain, kidney, lung, testicles. Transaminase is a major material basis in the body to promote the aminotransfer of proteins in its intermediate metabolism, while GOT can convert Asprate and ketoglutarate (A-ketoglutarate) The amino group and ketone group, and to synthesize new amino acids - Glutamate (Glutamate) and a new oxime-keto acid oxalacetate (Oxalacetate) its reaction: