论文部分内容阅读
目的:检测早期梅毒患者血清IL-37和IL-38的水平。方法:采用酶联免疫吸附法(ELISA)检测140例早期梅毒患者和180例正常对照血清IL-37、IL-38的表达水平。结果:早期梅毒患者血清中IL-37和IL-38的中位数分别为14.15 pg/m L和12.21 pg/m L,正常对照组分别为31.76 pg/m L和17.09 pg/m L,差异均有统计学意义(均P<0.005)。结论:早期梅毒患者外周血清中IL-37和IL-38降低,可能与梅毒患者细胞免疫相关。
Objective: To detect the serum levels of IL-37 and IL-38 in patients with early syphilis. Methods: The serum levels of IL-37 and IL-38 in 140 cases of early syphilis and 180 cases of normal controls were detected by enzyme-linked immunosorbent assay (ELISA). Results: The median serum levels of IL-37 and IL-38 in patients with early syphilis were 14.15 pg / m L and 12.21 pg / m L, respectively, and those in the normal control group were 31.76 pg / m L and 17.09 pg / m L, respectively All were statistically significant (P <0.005). CONCLUSION: IL-37 and IL-38 in the peripheral blood serum of patients with early syphilis decreased, which may be related to cellular immunity of syphilis patients.