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糖尿病肾病(diabetic Nephropathy,DN)是糖尿病(diabeticsMelitus,DM)常见和严重的并发症之一,临床上以DM患者出现持续性尿蛋白为主要标志,有20%~40%的DM患者最终发展为DN[1]。DM早期肾功能损害评价的直接指标是肾小球滤过率(glomerular Filtration Rate,GFR)。血清肌酐(serum
Diabetic nephropathy (DN) is one of the common and serious complications of diabetes mellitus (DM). Clinically, persistent urinary protein (DM) is the main marker in DM patients, and 20-40% of DM patients eventually develop into DN [1]. The direct indicator of early renal impairment in DM is glomerular Filtration Rate (GFR). Serum creatinine