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本文报道用 Ames 法对 SAGS 晶体盐红细胞保存液进行致突变研究。结果表明:在加或不加大鼠肝微粒体酶(S9)代谢活化条件下,SAGS 晶体盐红细胞保存液在0.02～100mg/ml 的6个剂量未发现阳性突变反应,即对 Ames 试验菌株无诱发基因点突变的作用。
In this paper, the Ames method was used to study the mutagenesis of SAGS crystalloid erythrocyte preservation solution. The results showed that there was no positive mutation reaction in SAGS crystalloid erythrocyte stock solution at 6 dosages of 0.02-100 mg / ml with or without addition of rat liver microsomal enzyme (S9) Induces gene mutation.