论文部分内容阅读
目的 研究儿童HP相关的各种疾病感染率及其与年龄之间分布关系。方法 上消化道症状就诊的 2 63例患儿 (男 15 1例 ,女 112例 ,最小 1 5岁 ,最大 14岁 ,平均 11 2岁 )。所有病例均做胃镜检查并行快速尿素酶试验 ,判断有无HP感染。结果 :慢性活动性胃炎阳性率最高 (67 9% ) ;慢性活动性胃炎与慢性浅表性胃炎差异显著 (χ2 =18 771,P <0 0 5 ) ;慢性活动性胃炎与溃疡差异显著 (χ2 =34 .993,P <0 0 5 ) ;胃炎与溃疡差异显著 (χ2=16 0 97,P <0 0 5 ) ;慢性浅表性胃炎与溃疡无显著性差异 (χ2 =3 698,P >0 0 5 )。结论 HP阳性率排序 :慢性活动性胃炎 >慢性浅表性胃炎 >胃溃疡 >十二指肠溃疡 ;HP感染是胃炎发病的重要影响因素 ,对慢性活动性胃炎影响程度最大 ,对慢性浅表性胃炎和溃疡的影响程度相对较小。儿童HP阳性总发生率及胃炎HP阳性率均低于国内成人 ,国外儿童HP阳性总发生率多数高于国内 ;HP阳性率随年龄增加而增加 ,以 12～ 14岁组为最高 ,临床不可忽视
Objective To investigate the prevalence of various HP-related diseases in children and its relationship with age distribution. Methods A total of 263 children (151 males and 112 females, the youngest 15 years old and the youngest 14 years old, mean 112 years) were enrolled in the study. All cases were gastroscopy and rapid urease test to determine whether HP infection. Results: The positive rate of chronic active gastritis was the highest (67.9%). There was significant difference between chronic active gastritis and chronic superficial gastritis (χ2 = 18.771, P <0.05). There was significant difference between chronic active gastritis and ulcer = 34.993, P <0.05). There was a significant difference between gastritis and ulcer (χ2 = 16 0 97, P <0 05). There was no significant difference between chronic superficial gastritis and ulcer (χ2 = 3 698, P> 0 0 5). Conclusion The positive rate of HP is ranked: chronic active gastritis> chronic superficial gastritis> gastric ulcer> duodenal ulcer; HP infection is an important factor in the pathogenesis of gastritis, which has the greatest influence on chronic active gastritis, The impact of gastritis and ulcers is relatively small. The total positive rate of HP in children and the positive rate of gastritis were lower than that in domestic adults. The positive rate of HP in children abroad was mostly higher than that in China. The positive rate of HP increased with the increase of age, which was the highest in 12 to 14 years old group