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目的探讨COPD并呼吸衰竭应用无创正压通气治疗的临床效果。方法回顾分析72例患者的临床资料。结果治疗组经BiPAP治疗48h后,患者自觉症状明显缓解,有效率(94%)高于对照组(75%),差异有统计意义(P<0.05)。两组治疗前pH、PaO2、PaCO2无显著性差异(P>0.05),治疗48h后,两组血气均有明显改善(P<0.05),但治疗组与对照组相比改变更加明显(P<0.05)。结论 BiPAP呼吸机在COPD合并呼吸衰竭的治疗上效果明显,值得临床应用。
Objective To investigate the clinical effect of noninvasive positive pressure ventilation in COPD with respiratory failure. Methods The clinical data of 72 patients were retrospectively analyzed. Results After treatment with BiPAP for 48 hours, the symptoms of patients were relieved obviously. The effective rate (94%) was higher than that of the control group (75%), the difference was statistically significant (P <0.05). There was no significant difference in pH, PaO2 and PaCO2 between the two groups before treatment (P> 0.05). After 48 hours of treatment, the blood gas of both groups were significantly improved (P <0.05), but the changes were more obvious in the treatment group and the control group (P < 0.05). Conclusion BiPAP ventilator is effective in the treatment of COPD with respiratory failure, which is worthy of clinical application.