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羟基喜树碱(Hydroxycamptothecin,HCPT)是抑制拓扑异构酶Ⅰ(TopoisomeraseⅠ)的药物,作用于S期,为细胞周期特异性药物,已被临床广泛应用。为探索较为合理的HCPT临床用药剂量,我们总结了自1998年3月我科含不同剂量HCPT(湖北黄石飞云制药有限公司产品)联合化疗治
Hydroxycamptothecin (HCPT) is a drug that inhibits Topoisomerase I and acts on S phase. It is a cell cycle-specific drug and has been widely used clinically. In order to explore a more reasonable dosage of HCPT for clinical use, we summarize our experience since March 1998 with different doses of HCPT (Hubei Huangshi Feiyun Pharmaceutical Co., Ltd.) combined with chemotherapy