Re-establishment of Spermatogenesis by Diethylstilbestrol after 2,5-Hexanedione-induced Irreversible

• 作 者: 钱悦 曾甫清
• 机 构: DepartmentofDermatology,DepartmentofUrology
• 出 处: Journal of Huazhong University of Science and Technology(Med
• 发表日期: 2008年2期
• 关键词: 精子 萎缩症 乙酚 重建机理 雌激素 spermatogenesis hexanedlone diethylstilbestrol testicular

To investigate the effects of diethylstilbestrol(DES) in reestablishing spermatogenesis and the mechanism by which estrogen works on spermatogenesis,rats were exposed to 1% 2,5-HD for 5 week.Then 0.1 mL of DES was given(s.c.) at a rate of 0.3 μg/kg,30 μg/