论文部分内容阅读
血样采于河南省食管癌高发区林县,鹤壁市和低发区范县的居民。年龄40～50岁的男女各半。林县人分无癌家族史和有癌家族史两组。林县食管癌标准化死亡率男性为161/10万,女性为102/10万;范县男性为26/10万,女性为7/10万;鹤壁市男性为128/10万,女性为 95/10万。 林县,范县受检者V_A水平0.3μg/ml左右,胡萝卜素0.45～1.29μg/ml。V_c水平低于2μg/ml者,林县占受检者的23％,范县只有16％。V_(B2)水平有90％的受检者AC大于1.20,50％的人在1.41～1.80之间。GSH含量随V_(B2)营养的改善而增高。鹤壁市居民有癌组,胡萝卜素水平低于正常组,增生组。V_A水平有癌组也低于增生组,均有显著差异。V_(B2)水平有70％受检者缺乏,增生组缺乏者竟达86.4％,提示V_(B2)在食管增生患者中,有较严重的缺乏。而吸烟能使V_C水平降低。 这次测定结果仅是对食管癌与维生素营养的关系作一初步了解。其中核黄素在食管癌高发区居民中缺乏较为广泛而严重。补充维生素及改良饮食习惯对防癌将有一定意义。
Blood samples collected in Henan Province, high incidence of esophageal cancer in Lin County, Hebi City and low incidence of Fan County residents. Men and women aged 40 to 50 years and a half. Linxian points cancer-free family history and cancer family history of two groups. The standardized death rate of esophageal cancer in Linlin County was 161/10 million for males and 102/10 for females; 26/10 for Fanxian County and 7/10 for females; 128/10 for men and 95 / 100,000. Lin County, Fan County subjects V_A level of about 0.3μg / ml, carotenoids 0.45 ~ 1.29μg / ml. Vc levels below 2μg / ml, Linxian accounted for 23% of subjects, Fanxian only 16%. V_ (B2) level 90% of the subjects AC greater than 1.20, 50% of the people in the 1.41 to 1.80 between. GSH content increased with the improvement of V (B2) nutrition. Residents of Hebi City have cancer, carotene levels lower than the normal group, hyperplasia group. V_A level of cancer group is also lower than the proliferation group, there are significant differences. V_ (B2) level of 70% of subjects lack of hyperplasia group was as high as 86.4%, suggesting that V B2 in patients with esophageal hyperplasia, there is a more serious lack of. Smoking can reduce the level of V_C. The measurement results only on esophageal cancer and vitamin nutrition to make a preliminary understanding of the relationship. Riboflavin in which high incidence of esophageal cancer in the lack of more extensive and serious. Vitamin supplements and improved diet will have some significance for cancer prevention.