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目的了解受种者对狂犬病疫苗“2-1-1”程序的依从性和接种后副反应,为推广使用“2-1-1”程序提供依据。方法对2012年1月~12月到福建省CDC门诊就诊的狂犬病暴露者按“2-1-1”程序接种疫苗,记录接种日期和接种后副反应,并比较分析。结果未成年和成年暴露者分别占24.2%和75.8%;平均依从率88.7%,以18~59岁组86.6%最低;Ⅲ级暴露者依从率90.5%高于Ⅱ级暴露的84.7%;依从率低的最常见原因是忘记接种日期。局部反应和全身反应分别以注射部位疼痛(3.1%)和发热(0.9%)最常见,发热多发生于首次接种后,主要为儿童。结论 “2-1-1”程序少就诊2次,可提高依从性,疫苗接种后发生的一般反应通常不需处理可自行好转,应积极推广使用。
Objective To understand the compliance of the rabies vaccine against “2-1-1” rabies vaccine and the post-vaccination side effects of the rabies vaccine, so as to provide basis for promoting the use of “2-1-1” program. Methods The rabies exposed to CDC clinic in Fujian province from January to December 2012 were vaccinated according to the procedure of “2-1-1”. The date of inoculation and the side effects after inoculation were recorded and compared. Results Minor and adult exposure accounted for 24.2% and 75.8% respectively. The average compliance rate was 88.7%, and the lowest was 86.6% in 18-59 years group. The compliance rate of grade Ⅲ exposure was 90.5% higher than that of grade Ⅱ exposure. The compliance rate The most common reason for low is forgetting the date of vaccination. Local and systemic reactions were most common at the site of injection pain (3.1%) and fever (0.9%), respectively, and fever mainly occurred in children after first vaccination. Conclusion “2-1-1 ” procedure less treatment twice, can improve compliance, the general reaction after vaccination usually do not need to deal with self-improvement should be actively promote the use of.