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本文首次报道黑龙江省海林县林区莱姆病的临床表现和流行病学特点。慢性游走性红斑的临床表现多种多样,典型环形红斑较少见,多数呈不同形状的红斑,有的中心起水泡或坏死。亦可出现继发性红斑。神经系统损害包括脑膜炎、面神经麻痹和多发性神经炎。心脏异常较少见。另外,还观察到皮肤良性淋巴细胞增生病。慢性游走性红斑的侵袭率为8.4%。男女性别的侵袭率有显著差别(P<0.05)。五、六两月为多发季节。患者都有蜱咬史。神经系统损害和关节炎的流行率分别为4.6%,6.6%。从临床表现、流行特点以及用恢复期病人血清检出了蜱中肠组织的螺旋体,可以认为当地存在莱姆病的自然疫源地。
This article first reported the clinical manifestations and epidemiological characteristics of Lyme disease in Hailin County, Heilongjiang Province. The clinical manifestations of chronic migratory erythema varied, the typical annular erythema is less common, the majority of different shapes of erythema, and some centers blisters or necrosis. Secondary erythema can also occur. Nervous system damage includes meningitis, facial paralysis and polyneuritis. Abnormal heart is rare. In addition, skin benign lymphoproliferative disease was also observed. The incidence of chronic migratory erythema was 8.4%. There was a significant difference in the prevalence of male and female sex (P <0.05). Five or six months for the multiple seasons. Patients have history of tick bites. The prevalence rates of nervous system damage and arthritis were 4.6% and 6.6% respectively. From the clinical manifestations, epidemiological characteristics and recovery of sera of tick ticks detected in the spirochetes, you can think of the local natural presence of Lyme disease.