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用圆二色光谱法研究了铜 ( )与 3,5 -二碘基 -L-酪氨酸 (L-I2 tyr) ,L-酪氨酸 (L-Tyr)或 L-高丝氨酸(L-Hser)和 L-/ DL-AA[AA代表精氨酸 (Arg) ,赖氨酸 (L ys) ,天冬酰胺 (Asn) ,谷氨酰胺 (Gln) ,或丙氨酸(Ala) ]三元混配配合物体系在不同离子强度 (I=1 .0或 0 .1 mol/ L KNO3)和溶剂环境 [水 ,5 0 % (体积分数 )乙醇 -水或 5 0 % (体积分数 )二氧六环 -水 ]条件下配合物分子内配体间相互作用 .全部混配配合物的圆二色谱在 5 99～ 6 2 3nm均有负的极大吸收 ,且 Cu(L-I2 tyr) (L-/ DL-Arg)和 Cu(L-I2 tyr) (L-/ DL-L ys)的 Δε异常负(-0 .493～ -1 .0 72 ) ;Cu(L-I2 tyr) (L-/ DL-AA)的 Δε明显比 Cu(L-Tyr) (L-/ DL-AA)负 .讨论了这些混配配合物中配体间相互作用的规律和碘的结构效应 .
The effects of copper (Ⅱ) and 3,5-diiodo-L-tyrosine (L-Tyr), L-tyr (L-Tyr) Hser) and L- / DL-AA [AA represents Arg, Lys, Asn, Gln, or Ala] Element mixture with different ionic strength (I = 1.0 or 0.1 mol / L KNO3) and solvent environment [water, 50% ethanol by volume or 50% Oxycyclohexane - water], the circular dichroism spectra of all the complexes were negatively absorbed at 5 99 ~ 6 2 3 nm, and Cu (L-I2 tyr) (Δ .493 ~ -1.702), Cu (L-I2 tyr) (L-DL tyrosine) and L-DL tyrosine Δε of L- / DL-AA was significantly lower than that of Cu (L-Tyr) (L- / DL-AA). The rules of ligand interactions and the structural effects of iodine in these complexes were discussed.