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目的:了解我院药品不良反应(ADR)的发生特点,促进临床合理用药。方法:对2004～2006年上报的258例ADRs分别从报告人、引发的药品种类、给药途径、临床表现等方面进行统计分析。结果:以护士和医师上报数量最多,占总例数的88.76%;与抗感染药有关的最为多见,占总例数的84.50%;给药方式以静脉滴注为主,占总例数的67.44%;表现以皮肤及附件为主,其次是消化系统损伤,其中较严重的有6例。结论:加强对抗感染药物合理应用的管理及监测工作十分必要。
Objective: To understand the characteristics of adverse drug reaction (ADR) in our hospital and to promote rational drug use in clinic. Methods: A total of 258 ADRs reported from 2004 to 2006 were analyzed statistically from the aspects of the reporter, the type of drug induced, the route of administration and the clinical manifestation. Results: The nurses and physicians reported the largest number, accounting for 88.76% of the total number of cases; the most common with anti-infectives, accounting for 84.50% of the total number of cases; mode of administration to intravenous infusion, the total number of cases Of the 67.44%; the performance of the skin and accessories based, followed by the digestive system damage, of which more serious in 6 cases. Conclusion: It is necessary to strengthen the management and monitoring of the rational use of anti-infective drugs.