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1983年1月~1994年12月12年间,经骨穿确诊收住小儿急性白血病(AL)208例。后6年较前6年增加了39%,其中ALL比ANLL为1.36:1,男比女为1.47:1,2~10岁组占61.06%,以L1和M2型最多。在确诊后、诱导中、巩固中放弃治疗者后6年较前6年有所减少,而维持强化和完成治疗者增多,其原因是采用了BFM方案加HD-MTX庇护所防治;组织培养了儿科血液专业医生。放弃治疗的根本原因是治疗费高、时间长;社会舆论、传媒导向对AL的悲观论调等也影响治疗的积极性。治疗时院内死亡19例,一半人死因与疾病未缓解或骨髓、脑白复发有关,部分人与化疗的毒副作用有关
From January 1983 to December 1994, 208 cases of infantile acute leukemia (AL) were diagnosed through the bones. After 6 years compared with the previous 6 years increased by 39%, ALL than ANLL was 1.36: 1, male than female 1.47: 1,2 to 10 years old group accounted for 61.06%, L1 and M2 type . After diagnosis, induction, consolidation to abandon the treatment of 6 years after 6 years compared with the previous 6 years decreased, while maintaining and enhancing the completion of the treatment increased, the reason is the use of the BFM program plus HD-MTX shelter prevention and treatment; tissue culture Pediatric blood specialist. Abandon the root cause of treatment is the high cost of treatment, a long time; public opinion, media-oriented AL pessimistic tone also affect the treatment of enthusiasm. Treatment of 19 cases of hospital deaths, half of the cause of death and disease did not alleviate or bone marrow, brain white recurrence related to the toxic side effects of some people with chemotherapy