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目的对广州市2例B群流行性脑脊髓膜炎(流脑)新生儿病例进行诊断并分析可能的传染源,为流脑预防控制提供依据。方法采用现场流行病学、血清学调查方法对流脑病例进行调查分析。结果 2例病例均因发热等症状入院,经抗生素治疗病情好转。病例的血标本及其密切接触者咽试子标本均分离到B群流脑菌株,该菌株对美罗培南、头孢西丁、头孢噻肟等敏感。结论本市近年来首次出现2例未满月婴幼儿感染B群流脑菌的病例,应加强流脑,尤其是B群流脑菌株病原学监测。
Objective To diagnose and analyze the possible sources of infection in 2 neonates with epidemic cerebrospinal meningitis (meningitis) of Group B in Guangzhou and provide the basis for prevention and control of meningitis. Methods Field epidemiological and serological methods were used to investigate the cases of meningioma. Results Two cases were admitted due to fever and other symptoms, the condition improved by antibiotics. The blood samples of patients and their close contact pharyngeal specimens were isolated B meningitis group strains, the strains of meropenem, cefoxitin, cefotaxime sensitive. Conclusions The cases of meningitidis B in two infants who were under full-fledged infants and young children were found in this city for the first time in recent years. Encephalitis, especially the meningococcal meningitis in group B, should be strengthened.