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目的分析韦格纳肉芽肿(WG)的临床特点以期提高本病的诊断水平。方法通过计算机系统网上查询对郑州大学第一附属医院和郑州人民医院1997-2009年住院收治并确诊为(WG)病的病例进行回顾性分析。结果WG病可累及多个系统和器官,主要侵犯肺脏、肾脏及上呼吸道,也可侵犯耳部、眼部、腮腺、口腔等部位。其c-ANCA阳性率高,病理表现多为坏死性肉芽肿炎症、炎细胞浸润的血管炎。结论WG的临床表现复杂多样,我们要熟悉韦格纳肉芽肿W G的临床特点,以期做到早期诊断,早期治疗。
Objective To analyze the clinical features of Wegener’s granulomatosis (WG) in order to improve the diagnosis of this disease. Methods A retrospective analysis was performed on the hospitalized and diagnosed (WG) patients admitted to the First Affiliated Hospital of Zhengzhou University and Zhengzhou People’s Hospital from 1997 to 2009 by computer system online query. The results of WG disease can affect multiple systems and organs, mainly invades the lungs, kidneys and upper respiratory tract, but also violations of the ear, eye, parotid, oral and other parts. The positive rate of c-ANCA, the pathological manifestations of mostly necrotizing granulomatous inflammation, inflammatory cell infiltration of vasculitis. Conclusion The clinical manifestations of WG are complex and diverse. We should be familiar with the clinical features of Wegener’s granulomatosis W G in order to achieve early diagnosis and early treatment.