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乙型肝炎病毒相关性肾炎（Hepatitis B virus associ-ated glomerulonephritis,HBV-GN）于1971年由Combes首先报道,在我国小儿肾小球疾病中所占比例为8.7％。我国于1989年正式命名,并归为肾小球疾病一种;其临床表现多样,儿童患病率高于成人,男多于女,成人患者预后远较儿童差。人类对该病的认识近30年,现就近年研究进展综述如下。1 发病机制与免疫病理1.1 发病机制 HBV-GN发病机制目前尚未完全清楚,综合文献有以下几种可能:①由于HBV感染后,病
Hepatitis B virus associated glomerulonephritis (HBV-GN) was first reported by Combes in 1971, accounting for 8.7% of pediatric glomerular diseases in our country. China officially named in 1989, and classified as a glomerular disease; its clinical manifestations of diverse, higher prevalence of children than adults, more men than women, adult patients prognosis is far worse than children. Nearly 30 years of human understanding of the disease, the research progress in recent years are summarized below. 1 pathogenesis and immune pathology 1.1 pathogenesis HBV-GN pathogenesis is not yet fully understood, the comprehensive literature has the following possibilities: ① due to HBV infection, the disease