论文部分内容阅读
目的探讨老年急性心肌梗死患者血清高敏C反应蛋白(hs-CRP)、尿酸(UA)水平及其与病情的相关性研究。方法选择80例老年急性心肌梗死患者为Ⅰ组,选择70例老年不稳定型心绞痛患者为Ⅱ组,选择60例老年稳定型心绞痛患者为Ⅲ组。比较3组患者血清hs-CRP及UA水平,并对hs-CRP与UA的相关性进行分析。结果Ⅰ组、Ⅱ组及Ⅲ组患者hs-CRP与UA依次降低,差别具有统计学意义(P<0.01);80例Ⅰ组患者中共有39例(48.8%)预后不良(死亡、心律失常及心力衰竭),预后不良患者hs-CRP与UA水平显著高于对照组,差别具有统计学意义(P<0.01);Ⅰ组与Ⅱ组患者血清hs-CRP与UA呈显著相关(P<0.05),而二者在Ⅲ组患者未见相关性(P>0.05)。结论高UA及hs-CRP是老年急性心肌梗死的独立危险因素,二者的联合检测对于预测老年急性心肌梗死的发生及预后具有重要价值。
Objective To investigate the correlation between serum hs-CRP and uric acid (UA) in elderly patients with acute myocardial infarction. Methods Eighty elderly patients with acute myocardial infarction were selected as group Ⅰ, 70 patients with unstable angina pectoris were selected as group Ⅱ, and 60 elderly patients with stable angina pectoris were selected as group Ⅲ. The serum levels of hs-CRP and UA in the three groups were compared, and the correlation between hs-CRP and UA was analyzed. Results The levels of hs-CRP and UA in group Ⅰ, group Ⅱ and group Ⅲ were significantly lower than those in group Ⅲ (P <0.01). There were 39 patients (48.8%) in group Ⅰ with poor prognosis (death, arrhythmia, (P <0.01). The serum levels of hs-CRP and UA in group Ⅰ and group Ⅱ were significantly correlated with UA (P <0.05), and the levels of hs-CRP and UA in patients with poor prognosis were significantly higher than those in control group , While there was no correlation between them in group Ⅲ (P> 0.05). Conclusions High UA and hs-CRP are independent risk factors for senile acute myocardial infarction. The combined detection of them is of great value in predicting the occurrence and prognosis of elderly patients with acute myocardial infarction.