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为了解炎性肠病的治疗变迁,本文随访分析了该院1958~1994年间收治的溃疡性结肠炎193例,对比了前20年和近17年的发病情况和治疗效果。发现近10余年诊治该病由年平均4例.上升达6.6例;但重症或转外科治疗的病例明显减少,未再出现合并肠穿孔或中毒性巨结肠病例。近90%病人经内科治疗痊愈或好转,外科手术死亡率前20年为43%(9/21),1978年后无1例死亡(0/6)。作者认为,近年治疗效果的提高,除一般病人体质改善外,与抗菌药物趋向完善,充分的静脉营养支持和选择恰当的手术方式有关。
In order to understand the therapeutic changes of inflammatory bowel disease, this paper analyzed 193 cases of ulcerative colitis treated in our hospital from 1958 to 1994, and compared the incidence and treatment effect in the first 20 years and the past 17 years. Found nearly 10 years diagnosis and treatment of the disease by an average of 4 cases. Up to 6.6 cases; but severe or surgical cases were significantly reduced, no recurrence of intestinal perforation or toxic Hector cases. Nearly 90% of the patients were cured or improved after medical treatment. The surgical mortality rate was 43% (9/21) in the first 20 years and none in 1978 (0/6). The author believes that the improvement of the therapeutic effect in recent years, in addition to improving the general patient’s physical fitness, and antimicrobial drugs tend to improve, adequate intravenous nutritional support and choose the appropriate surgical approach.