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目的探讨胆固醇(TC)、甘油三酯(TG)含量与病毒灭活冰冻血浆物理外观的相关性。方法采用尿液外观理学检查法观察血浆浑浊度,4℃静置过夜法观察血浆乳糜,全自动生化仪分析仪测定TC和TG含量。结果1)223份病毒灭活冰冻血浆中,32份(14.35%)血浆出现TG升高和乳糜现象,未出现TC升高现象。2)血浆清亮、轻度混浊、混浊、重度混浊组间TC差异无统计学意义(P>0.05),而TG差异有统计学意义(P<0.05)。3)乳糜组与非乳糜组间TC差异无统计学意义(P>0.05),而TG差异有统计学意义(P<0.05)。结论血浆TG含量与病毒灭活冰冻血浆物理外观呈正相关,建议常规增加血浆TG含量检测,以有效降低血浆物理外观的临床报废率,保护血液资源。
Objective To investigate the correlation between cholesterol (TC), triglyceride (TG) content and the physical appearance of virus inactivated frozen plasma. Methods The appearance of plasma turbidity was observed by the method of urinalysis and the plasma was collected at 4 ℃ overnight. The contents of TC and TG were determined by automatic biochemical analyzer. Results 1) In 223 serum-inactivated frozen plasma, 32 (14.35%) of the plasma showed TG increase and chyle phenomenon, no increase of TC appeared. There was no significant difference in TC between the two groups (P> 0.05), but the difference of TG was statistically significant (P <0.05). 3) There was no significant difference in TC between chylomicrons and non-chylomicrons (P> 0.05), but there was significant difference in TG (P <0.05). Conclusions There is a positive correlation between the content of plasma TG and the physical appearance of virus inactivated frozen plasma. It is suggested to increase the content of plasma TG in order to effectively reduce the clinical rejection rate of plasma physical appearance and to protect the blood resources.