Ursodeoxycholic acid and superoxide anion

• 作 者: Predrag Ljubuncic Omar Abu-Sal
• 机 构: DepartmentofPharmacology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2005年31期
• 关键词: 熊脱氧胆酸 过氧化阴离子 原发性胆硬化 病理机制 Ursodeoxycholic acid Superoxide anion Antioxidant

AIM: To investigate the ability of ursodeoxycholic acid (UDCA) to scavenge superoxide anion (O2-).METHODS: We assessed the ability of UDCA to scavenge (O2-) generated by xanthine-xanthine oxidase (X-XO) in a cell-free system and its effect on the rate of