产前诊断胎儿Dandy-Walker综合征一例报道

• 作 者: 毛娟虹 法韫玉
• 机 构: 上海第二医科大学附属第九人民医院妇产科!200011,上海第二医科大学附属第九人民医院妇产科!200011
• 出 处: 上海第二医科大学学报
• 发表日期: 1997年05期
• 关键词: 产前诊断 Dandy-Walker 染色体异常 颅外畸形 发育异常 小脑延髓池 终止妊娠 蚓部 第四脑室 宫内诊断

产前诊断胎儿Dandy－Walker综合征一例，该综合征系先天性颅内发育异常，也可伴有多种颅外畸形和染色体异常，其病因尚未明了，可能与宫内病毒或弓形体感染、服药和饮酒有关。该综合征预后极差，产后死亡率41％～55％，在存活者中均有不同程度的智力发育障碍或残疾。B超对妊娠20周左右的Dandy－Walker综合征能确诊，及时终止妊娠，对优生优育具有重要意义。

Prenatal diagnosis of fetal Dandy-Walker syndrome, a syndrome of the syndrome Department of congenital intracranial dysplasia can also be associated with a variety of extracranial deformities and chromosomal abnormalities, the etiology is not yet clear, may be associated with intrauterine virus or toxoplasmosis, Medication and alcohol related. The syndrome has a very poor prognosis with a postpartum mortality rate of 41% to 55%, with varying degrees of mental retardation or disability in survivors. B-ultrasound about 20 weeks of pregnancy Dandy-Walker syndrome can be diagnosed, timely termination of pregnancy, prenatal and postnatal care is of great significance.