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为探讨麻疹疫苗再免疫的效果,对珠海市香洲区按免疫程序8月龄、3岁、7岁进行麻疹疫苗(MV)接种的3岁、7岁儿童共196人,进行了再免疫效果评价。结果表明:再免疫前、后麻疹抗体阳性率分别为96.43%和100%,几何平均滴度(GMT)分别为1:805和1:4557。再免疫成功率与再免疫前抗体滴度呈负相关,再免疫前抗体滴度<1:200、1:200、1:800、1:3200的,再免疫成功率分别为100%、97.06%、94.07%、71.88%;3岁与7岁间再免疫成功率的差异无显著的统计学意义.初免(8月龄)后2年、再免疫(3岁)后4年,麻疹抗体滴度均处在低抗体水平,显示麻疹再免疫具有重要的意义,再免疫年龄3岁比较合适.
In order to explore the effect of re-immunization of measles vaccine, re-immunization was evaluated on a total of 196 children aged 3 and 7 years old who were immunized with measles vaccine at 8 months, 3 years and 7 years of age in Xiangzhou District, Zhuhai City. . The results showed that the positive rates of measles antibody before and after re-immunization were 96.43% and 100%, respectively. The geometric mean titers (GMTs) were 1: 805 and 1: 4557, respectively. The success rate of re-immunization was negatively correlated with the antibody titer before re-immunization. The antibody titer <1: 200, 1: 200, 1: 800 and 1: 3200 before reimmunization was 100% and the re-immunization success rates were 97.06% , 94.07% and 71.88% respectively. No significant difference was found in the success rate of re-immunization between 3 years and 7 years old. Measles antibody titer at 2 years after initial immunization (8 months old), 2 years after immunization (3 years old) and 4 years after immunization (3 years old) showed that immunization with measles was of great significance.