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抑制性T细胞(Ts细胞)是T细胞亚群之一,它是机体免疫反应的调节细胞,既能抑制体液免疫反应,也能抑制细胞免疫反应,是自身稳定机能的重要因素。在肿瘤免疫中Ts细胞具有重要作用,它可破坏抗肿瘤反应,并促进肿瘤生长。本文拟就Ts细胞在肿瘤免疫中的作用,作一简述。一、Ts细胞的表面标志 1、表面抗原:从小鼠实验证实,在胸腺腺体中,大多数鼠淋巴细胞表面抗原是Ly1,2,3+,TL+及Thy-1+。随着进一步成熟,TL表面抗原消失;Ly1,2,3+细胞分成两个T细胞亚群,带有Ly1+为
Suppressing T cells (Ts cells) is one of the T cell subsets. It is a regulator of the immune response of the body. It inhibits the humoral immune response as well as the cellular immune response and is an important factor in its own stabilizing function. Ts cells play an important role in tumor immunity, which can destroy anti-tumor responses and promote tumor growth. This article intends to Ts cells in the role of tumor immunity, make a brief description. First, the surface markers of Ts cells 1, surface antigen: experiments from mice confirmed that in the thymic gland, most of the mouse lymphocyte surface antigen Ly1,2,3 +, TL + and Thy-1 +. As further maturation, TL surface antigens disappeared; Ly1,2,3 + cells were divided into two subsets of T cells with Ly1 +