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在巴塞尔心梗存活者抗心律失常研究(BASIS)中发现,小剂量胺碘酮可提高心梗后持续2周而无症状的复杂室性心律失常患者的1年生存率。为了评估在停用胺碘酮1年后这种有益作用能否持久,作者对胺碘酮治疗组(n=98)和对照组(n=114)共212例患者的远期结果进行了评价。方法本文采用BASIS的研究方法,将出院时仍有持续性无症状复杂室性心律失常的心梗成活患者随机分成两组:小剂量胺碘
In BASIS, the Basel anti-arrhythmic study (BASIS) found that low-dose amiodarone increased 1-year survival in patients with complex asymptomatic arrhythmia lasting 2 weeks after MI. To assess the long-lasting beneficial effects of amiodarone 1 year after discontinuation of amiodarone, the authors evaluated the long-term outcomes of 212 patients in the amiodarone group (n = 98) and the control group (n = 114) . Methods In this study, BASIS was used to divide patients with myocardial infarction who had persistent asymptomatic complex ventricular arrhythmias at discharge into two groups: low-dose amiodarone