论文部分内容阅读
目的 :观察大肠癌患者术前术后血清脂蛋白、血脂、癌胚抗原的变化。方法 :对 46例大肠癌病人和 40例正常人检测血清TC、TG、HDL C、LDL C、CEA术前术后的改变。结果 :术前大肠癌血清TC和HDL C水平明显低于正常组 ,CEA水平明显高于正常组 ,差异非常显著 (P <0 .0 1) ;术后大肠癌血清TC、HDL C、CEA水平与正常组对照有显著差异 (P <0 .0 5 ) ,大肠癌恶性程度高则血清TC和HDL C水平与正常人的差异有显著意义 (P <0 .0 1)。结论 :血清TC、HDL C和CEA的测定 ,对大肠癌的分期、预后有指导意义。
Objective: To observe the changes of serum lipoprotein, lipids and carcinoembryonic antigen in patients with colorectal cancer before and after operation. Methods: The changes of serum TC, TG, HDL C, LDL C and CEA before and after operation in 46 patients with colorectal cancer and 40 normal persons were detected. Results: The serum levels of TC and HDL C in preoperative colorectal cancer were significantly lower than those in normal group, and the levels of CEA were significantly higher than those in normal group (P <0.01). The levels of TC, HDL C, CEA There was a significant difference between the control group and the normal control group (P <0.05). The high malignant degree of colorectal cancer was associated with the difference of serum TC and HDL C levels (P <0.01). Conclusion: The determination of serum TC, HDL C and CEA has guiding significance for the staging and prognosis of colorectal cancer.