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目的探讨双歧杆菌乳杆菌三联活菌、葡萄糖酸锌治疗婴幼儿抗生素相关性腹泻的疗效。方法将澄江县妇幼保健院收治的81例诊断为抗生素相关性腹泻的婴幼儿随机分为两组,治疗组40例,对照组41例。两组均采用常规治疗方法,治疗组同时加用双歧杆菌乳杆菌三联活菌、葡萄糖酸锌治疗,以大便次数、腹泻持续时间及治愈率作为客观评价指标。结果治疗组较对照组便次明显降低(P<0.05);腹泻持续时间明显缩短(P<0.05);治疗组治愈率为80.0%,对照组为46.34%,治疗组明显高于对照组(P<0.05)。结论婴幼儿抗生素相关性腹泻在常规治疗基础上,加用双歧杆菌乳杆菌三联活菌及葡萄糖酸锌口服可有效改善临床症状,缩短病程,提高疗效,值得推广。
Objective To investigate the efficacy of Lactobacillus bifidum triple live bacteria and zinc gluconate in the treatment of antibiotic-associated diarrhea in infants. Methods 81 cases diagnosed as antibiotic-associated diarrhea admitted to Chengjiang MCH hospital were randomly divided into two groups: treatment group (40 cases) and control group (41 cases). The two groups were treated with conventional treatment, the treatment group also added Lactobacillus bifidosis triple live bacteria, zinc gluconate treatment, stool frequency, diarrhea duration and cure rate as objective evaluation. Results The treatment group was significantly lower than the control group (P <0.05), diarrhea duration was significantly shorter (P <0.05), the cure rate was 80.0% in the treatment group and 46.34% in the control group, the treatment group was significantly higher than the control group (P <0.05). Conclusion Antibiotic-associated diarrhea in infants and young children on the basis of routine treatment, plus Bifidobacterium Lactobacillus triple oral and oral zinc gluconate can effectively improve clinical symptoms, shorten the course of the disease and improve the efficacy, it is worth promoting.