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目的:探索接触n 131I放射性核素放射工作人员内照射剂量估算方法。n 方法:选择某n 131I放射性药物生产企业和某开展n 131I甲亢和甲状腺癌治疗的医院核医学科放射工作人员，使用便携式高纯锗(HPGe)γ谱仪，以7 d为周期，连续4次测量甲状腺部位n 131I活度，结合人员接触n 131I的轮岗方式，估算内照射剂量。n 结果:以监测月份为典型月份估算人员内照射剂量时，调查企业从事n 131I放射性药物分装的生产人员年待积有效剂量为0.09~1.93 mSv，调查医院核医学科工作人员内照射年待积有效剂量为0.06~0.58 mSv。对监测结果进行校正和结合轮岗方式后估算的工作人员内照射年待积有效剂量，放射性药物生产工作人员和核医学科工作人员分别为0.06~1.22 mSv和0.03~0.16 mSv。n 结论:在进行接触n 131I放射性核素工作人员内照射剂量估算时，仅以单次测量的结果估算全年受照剂量会带来较大的误差。在连续监测时，应根据前续监测周期的结果对后续监测周期结果进行校正。为准确估算人员内照射剂量，应充分考虑工作人员接触n 131I的方式、接触的时间、接触的频率、内污染的途径等因素。对于接触n 131I内照射剂量可能>1 mSv/年的工作人员，以14 d作为常规监测周期较为适宜。n “,”Objective:To explore the assessment methodology for internal dose to workers exposed to n 131I radionuclide.n Methods:Workers were chosen in a n 131I radiopharmaceutial manufacturer and a nuclear medicine department in a hospital using n 131I to treat hyperthyroidism and thyroid cancer. A portable high purity germanium (HPGe) gamma spectrometer was used to measure the content of n 131I in the thyroid for 4 consecutive times in a period of 7 d. The internal dose was estimated combining with the work rotation mode for workers dealing with n 131I.n Results:When the monitoring month was used as a typical month to estimate the internal dose, the annual committed effective dose was 0.09-1.93 mSv for the production staff engaged in the repackaging of n 131I radiopharmaceuticals in the surveyed enterprise, and 0.06-0.58 mSv for the nuclear medicine staff in the surveyed hospital. After adjusting the monitoring result of the current monitoring period based on the rotation mode, the annual committed effective dose was estimated to be 0.06-1.22 mSv for radiopharmaceutical production workers and 0.03-0.15 mSv for nuclear medicine workers, respectively.n Conclusions:In the assessment of internal dose to radiation workers exposed to n 131I, using a single time measurement result to estimate the annual dose would lead to a larger error. In the case of continuous monitoring, the result of subsequent monitoring periods should be corrected according to the result of previous monitoring periods. In order to accurately estimate the internal dose of workers exposed to n 131I, it is necessary to take full account of the n 131I exposure pattern, time and frequency and the internal contamination route. For workers who may be exposed to n 131I with potential internal dose greater than 1 mSv/year, a 14 day-routine monitoring period was appropriate.n