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目的探讨早期吞咽功能训练对鼻咽癌放疗患者功能恢复及生活质量的影响。方法选取2010年1月至2015年7月间接受治疗的52例鼻咽癌放疗患者,根据随机数字法将其分为观察组和对照组,每组26例。观察组患者在常规治疗基础上,早期加用吞咽功能训练,对照组患者仅采用常规治疗。比较两组患者治疗前后吞咽功能的变化情况,以及放疗的临床疗效、吸入性肺炎发生率。根据生活质量测定量表(EORTC-QLQ-C30),评估和比较治疗前后患者生活质量各维度得分及总分变化情况。结果与对照组比较,观察组患者治疗后吞咽功能得到了明显改善,差异有统计学意义(P<0.05)。与对照组比较,观察组患者总有效率明显提高,吸入性肺炎发生率显著降低,差异有统计学意义(P<0.05)。与对照组比较,观察组患者治疗后生活质量各维度得分及总分均明显增高,差异有统计学意义(P<0.05)。结论早期吞咽功能训练有助于鼻咽癌放疗患者吞咽功能的恢复,明显提高放疗的临床疗效及生活质量。
Objective To investigate the effect of early swallowing functional training on functional recovery and quality of life of patients with nasopharyngeal carcinoma undergoing radiotherapy. Methods Fifty-two patients with nasopharyngeal carcinoma received radiotherapy between January 2010 and July 2015 were randomly divided into observation group and control group, with 26 cases in each group. Patients in the observation group were treated with swallowing function early on the basis of conventional treatment, while patients in the control group were treated only routinely. The changes of swallowing function before and after treatment were compared between two groups, as well as the clinical efficacy of radiotherapy and the incidence of aspiration pneumonia. According to the quality of life measurement scale (EORTC-QLQ-C30), the scores and total scores of quality of life before and after treatment were evaluated and compared. Results Compared with the control group, the swallowing function of the observation group was significantly improved after treatment, the difference was statistically significant (P <0.05). Compared with the control group, the total effective rate in the observation group was significantly increased, and the incidence of aspiration pneumonia was significantly lower (P <0.05). Compared with the control group, the score of the quality of life and the total score of the quality of life in the observation group were significantly increased, the difference was statistically significant (P <0.05). Conclusion Early swallowing functional training is helpful for the recovery of swallowing function of patients with nasopharyngeal carcinoma radiotherapy and significantly improves the clinical efficacy and quality of life of radiotherapy.