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分析 1981年至 2 0 0 1年 2 0年间北京市部分职业人群血清总胆固醇水平的变化。在力求做到血脂测定标准化的基础上 ,回顾性分析 2 0年来北京市部分机关和企事业单位工作人员 47434人次总胆固醇水平的变化 ,按年度、性别、年龄分组统计。结果发现 ,总胆固醇水平从 1981年至 1988年间上升幅度较大 ,年龄调整均值男性上升0 .73mmol/L (2 8mg/dL) ,女性上升 0 .6 2mmol/L (2 4mg/dL)。至 1990年已达最高值 ,2 0 0 1年低于 1991年 ,男、女年龄调整均值分别回落 0 .2 1mmol/L (8mg/dL)及 0 .2 3mmol/L (9mg/dL)。男女总胆固醇水平随年龄上升 ,从青年至老年 ,男性上升约 2 0 %,而女性升高达 35 %,上升趋势基本一致。不同年龄组间上升幅度有明显的男女差异 ,青年期男性大于女性 ,中年以后女性上升幅度增大 ,从 40～ 49岁至 5 0～ 5 9岁组男性平均上升 3%,而女性上升达 14%,6 0岁以后上升很少。所以总胆固醇水平在 5 0岁以前男性高于女性 ,5 0岁以后女性高于男性。以 1985年、1991年和 2 0 0 1年为例 ,无论男女 ,年龄标化的高胆固醇检出率 [总胆固醇≥ 5 .17mmol/L (2 0 0mg/dL)、≥ 5 .6 9mmol/L (2 2 0mg/dL)及≥ 6 .0 2mmol/L (2 40mg/dL) ]1991年比 1985年明显增高 ,而 2 0 0 1年与 1991年相差不多且有所回落
The changes of serum total cholesterol levels in some occupational groups in Beijing from 1981 to 2001 were analyzed. On the basis of striving to achieve the standardization of blood lipids, the changes of total cholesterol in 47,434 people in some organs and enterprises in Beijing in 20 years were retrospectively analyzed, and the statistics were grouped by year, sex and age. The results showed that the total cholesterol level increased significantly from 1981 to 1988, the average age-adjusted male rose 0.73mmol / L (28mg / dL), women rose 0.62mmol / L (24mg / dL). Reaching the highest level in 1990 and lower in 2001 than in 1991, with the mean adjustment of male and female ages falling back to 0.21 mmol / L (8 mg / dL) and 0.23 mmol / L (9 mg / dL), respectively. The total cholesterol level of men and women increased with age. From youth to the elderly, men increased by about 20%, while women increased by 35%. The upward trend was basically the same. There was a significant difference between men and women in different age groups. The number of adolescent men was greater than that of women. The increase rate of mid-aged women increased from 3 to 40% from 40 to 49 years old to 50 to 59 years old group, while the female up to 14%, little increase after 60 years of age. So the level of total cholesterol is higher in males than in males before the age of 50 and in females after 5 0 are higher than those in males. Taking 1985, 1991 and 2001 as examples, the age-standardized high cholesterol detection rate [total cholesterol ≥5.17 mmol / L (200 mg / dL), ≥5.69 mmol / L (220 mg / dL) and ≥6.0 2 mmol / L (240 mg / dL) in 1991 were significantly higher than those in 1985, but they were similar in 2001 and somewhat lower in 1991