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本文报道了近10年鼻咽癌放射治疗后出现眼部损伤13例（14只眼），其中鼻咽癌Ⅱ期7例，Ⅲ期6例．放射性白内障3例（4只眼），视网膜病变5例．视神经病变4例，合并白内障1例．发病时间为单程放疗后3年-6年，再程放疗后2年4个月-3年9个月．经临床及CT检查均排除鼻咽癌的复发和转移．发病原因均系由射线直接引起晶状体囊下上皮细胞损伤和放射性血管损伤所致，与放射野的设置、总放射量、分割剂量、存活时间、肿瘤的复发、个人身体状况等多种因素有关．我们认为预防和减少本病的发生，根据临床具体情况，周密制定放疗方案，对随访复查病人眼部检查应列为常规项目．同时对发病机理，眼部表现，治疗方法等进行了简单的讨论．
This article reports 13 cases (14 eyes) of ocular injury after radiotherapy of nasopharyngeal carcinoma in recent 10 years, including 7 cases of stage Ⅱ nasopharyngeal carcinoma and 6 cases of stage Ⅲ. 3 cases of radiation cataract (4 eyes), 5 cases of retinopathy. 4 cases of optic neuropathy, 1 case of cataract. Incidence of one-way radiotherapy after 3 years - 6 years, 2 years and 4 months after re-radiotherapy - 3 years and 9 months. The clinical and CT examination exclude nasopharyngeal carcinoma recurrence and metastasis. The causes are caused by the rays directly caused by lens capsule subepithelial cell damage and radiation-induced vascular injury, and the setting of the radiation field, the total radiation, divided doses, survival time, tumor recurrence, personal physical condition and other factors. We believe that the prevention and reduction of the occurrence of this disease, based on clinical specific circumstances, well-developed radiotherapy program, follow-up review of patients with eye examination should be classified as a routine project. At the same time on the pathogenesis, eye performance, treatment methods were briefly discussed.