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目的:观察岩舒注射液联合微波热疗治疗晚期恶性肿瘤的临床疗效。方法:75例患者随机分为2组,治疗组45例,采用岩舒注射液联合微波热疗;对照组30例,常规治疗联合微波热疗。比较2组近期疗效、疼痛缓解程度、改善生活质量及预防骨髓、肝肾功能损害等方面。结果:有效率(CR+PR)治疗组为37.7%,对照组为20.0%,2组比较,差异有显著性意义(P<0.05);总好转率(CR+PR+NC)治疗组为68.8%,对照组为56.7%,2组比较,差异有显著性意义(P<0.05)。疼痛缓解率治疗组为55.6%,对照组为33.4%,2组比较,差异有显著性意义(P<0.05)。2组外周血白细胞比较,差异有显著性意义(P<0.05);2组在血红蛋白、血小板、肝功能、肾功能方面比较,差异无显著性意义(P>0.05)。结论:岩舒注射液与微波热疗联合治疗晚期恶性肿瘤具有较好的临床疗效。
Objective: To observe the clinical effect of Yan Shu injection and microwave hyperthermia in the treatment of advanced malignant tumors. Methods: Seventy-five patients were randomly divided into two groups. The treatment group (n = 45) received Yan Shu injection combined with microwave hyperthermia. The control group (n = 30) received conventional microwave hyperthermia. Compare the two groups of recent efficacy, pain relief, improve quality of life and prevent bone marrow, liver and kidney dysfunction and so on. Results: The effective rate (CR + PR) in the treatment group was 37.7% and in the control group was 20.0%, there was significant difference between the two groups (P <0.05). The total improvement rate (CR + PR + %, 56.7% in the control group, the difference between the two groups was significant (P <0.05). The pain relief rate was 55.6% in the treatment group and 33.4% in the control group. There was significant difference between the two groups (P <0.05). There was no significant difference in hemoglobin, platelet, liver function and renal function between the two groups (P> 0.05). There was no significant difference between the two groups (P> 0.05). Conclusion: Yan Shu injection combined with microwave hyperthermia in the treatment of advanced malignant tumors has a good clinical effect.