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慢性氟中毒是因为长期服用含氟或者氟化物导致氟超过生理需要量所导致的中毒病,会导致不同程度的听觉障碍,造成听力下降、耳聋耳鸣等临床症状且尚未有研究对造成该临床症状的原因进行确切的解释[1]。本研究通过对大鼠建立氟中毒模型,测定大鼠听觉脑干诱发反应变化特点从而为探讨慢性氟中毒大鼠听力损伤机制提供依据,具体研究报道如下:1材料与方法1.1实验仪器与材料1.1.1实验仪器T125D电子分析天平(德国赛多利
Chronic fluorosis is due to long-term use of fluoride or fluoride lead to fluoride than physiological requirements caused by poisoning, can lead to varying degrees of hearing impairment, resulting in hearing loss, deafness and other clinical symptoms of tinnitus and has not been studied for the cause of the clinical symptoms The exact reason for the explanation [1]. In this study, fluorosis model was established in rats to measure the characteristics of auditory brainstem response in rats so as to provide evidence for the mechanism of hearing impairment in rats with chronic fluorosis. The specific reports are as follows: 1 Materials and methods 1.1 Experimental equipment and materials 1.1 .1 Experimental Instrument T125D electronic analytical balance (Sartorius Germany