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目的:观察健脾化湿、活血解毒法配合介入治疗原发性肝癌的临床疗效。方法:将60例患者随机分为2组,对照组20例,采用介入治疗;治疗组40例,在介入治疗的基础上同时服用健脾化湿、活血解毒中药(处方:太子参、白术、山药、茵陈、薏苡仁、莪术、石打穿、半枝莲)。1月为1疗程,连续2疗程后观察2组近期疗效、临床症状缓解情况及不良反应。结果:在近期疗效方面,2组有效率比较,差异无显著性意义(P>0.05),但2组稳定率比较,差异有显著性意义(P<0.05);临床症状改善率治疗组为90%,对照组为70%,2组比较,差异有显著性意义(P<0.05);不良反应发生率方面,治疗组明显低于对照组。结论:健脾化湿、活血解毒法配合介入治疗原发性肝癌,可改善病情,延长疾病进展时间,缓解临床症状,改善生活质量,并减轻介入治疗的不良反应。
Objective: To observe the clinical curative effect of invigorating the spleen, dampness, promoting blood circulation and detoxification in interventional therapy of primary liver cancer. Methods: Sixty patients were randomly divided into two groups, 20 cases in the control group were treated by interventional therapy. In the treatment group, 40 cases were treated with the drugs of invigorating the spleen and dampness, promoting blood circulation and detoxifying simultaneously (prescription: Radix Pseudascal, Atractylodes, Yam, capillaris, Coix seed, Curcuma, stone punch, Scutellaria barbata). January for a course of treatment, after 2 consecutive courses of treatment observed two groups of recent efficacy, clinical symptoms and adverse reactions. Results: There was no significant difference between the two groups in effective rate (P> 0.05), but there was significant difference between the two groups (P <0.05). The clinical symptom improvement rate was 90 %, The control group was 70%, the difference between the two groups was significant (P <0.05); adverse reaction rate, the treatment group was significantly lower than the control group. Conclusion: The treatment of invigorating the spleen and dampness, promoting blood circulation and detoxification combined with interventional treatment of primary liver cancer can improve the condition, prolong the time of disease progression, relieve the clinical symptoms, improve the quality of life and relieve the adverse reactions of interventional therapy.